- 1 Scope
- 2 How to improve the glossary
- 3 Principles governing content
- 4 Defined Concepts
- 4.1 Allele Fixation
- 4.2 Analogy
- 4.3 Ancestor
- 4.4 Apomorphy
- 4.5 Atavism
- 4.6 Bifurcation
- 4.7 Bipartition
- 4.8 Bootstrap Support
- 4.9 Branch
- 4.10 Branch Support
- 4.11 Character
- 4.12 Character-State
- 4.13 Character-State Data Matrix
- 4.14 Clade
- 4.15 Cladogram
- 4.16 Contrasts
- 4.17 Convergence
- 4.18 Convergent Evolution
- 4.19 CpG Bias
- 4.20 Deletion
- 4.21 Derived
- 4.22 Descendant
- 4.23 Dichotomy
- 4.24 Distance Matrix
- 4.25 Dollo Parsimony
- 4.26 Drift
- 4.27 Edge
- 4.28 Evolutionary Transition
- 4.29 Fixation
- 4.30 Fully Resolved
- 4.31 Gap
- 4.32 General Time-Reversible Model (GTR)
- 4.33 Genome Hypothesis
- 4.34 HGT
- 4.35 Homology
- 4.36 Homoplasy
- 4.37 Holophyly
- 4.38 Horizontal Gene Transfer (HGT)
- 4.39 HTU
- 4.40 Hypothetical Taxonomic Unit
- 4.41 Indel
- 4.42 Insertion
- 4.43 Lateral Gene Transfer
- 4.44 Leaf node
- 4.45 LGT
- 4.46 Likelihood Method
- 4.47 Lineage
- 4.48 Molecular Clock
- 4.49 Monophyly
- 4.50 Most Recent Common Ancestor
- 4.51 MRCA
- 4.52 Mutation
- 4.53 Mutation Bias
- 4.54 Natural Selection
- 4.55 Neighbor-Joining Algorithm
- 4.56 Network
- 4.57 Neutral
- 4.58 Nucleotide Transition
- 4.59 Nucleotide Transversion
- 4.60 Operational Taxonomic Unit
- 4.61 Organismal Taxonomy
- 4.62 Orthology
- 4.63 OTU
- 4.64 Outgroup
- 4.65 Parallel Evolution
- 4.66 Paralogy
- 4.67 Paraphyly
- 4.68 Parsimony Method
- 4.69 Phylogenetic Tree
- 4.70 Phylogenetic Tree Topology
- 4.71 Phylogeny
- 4.72 Phylogeny Inference Method
- 4.73 Plesiomorphy
- 4.74 Polymorphism
- 4.75 Polyphyly
- 4.76 Polytomy
- 4.77 Primitive
- 4.78 Random Genetic Drift
- 4.79 Rank
- 4.80 Reconcile Tree
- 4.81 Reconstruction
- 4.82 Replacement
- 4.83 Reversion
- 4.84 Reversal
- 4.85 Root
- 4.86 Selection
- 4.87 Sequence Family
- 4.88 Silent
- 4.89 Species Tree
- 4.90 State
- 4.91 Step Matrix
- 4.92 Substitution
- 4.93 Subtree
- 4.94 Supertree
- 4.95 Symplesiomorphy
- 4.96 Synapomorphy
- 4.97 Synonymous
- 4.98 Taxon
- 4.99 Taxonomic Rank
- 4.100 Taxonomy
- 4.101 Terminal Node
- 4.102 Topology
- 4.103 Trait
- 4.104 Transition, disambiguation
- 4.105 Transition Model
- 4.106 Tree
- 4.107 Unresolved
- 5 Undefined concepts
- 5.1 Anagenesis
- 5.2 Basal
- 5.3 Cladogenesis
- 5.4 Coalescent
- 5.5 Codon Usage
- 5.6 Compatibility
- 5.7 Consensus Tree
- 5.8 Conservative
- 5.9 Constraint
- 5.10 Cost Matrix
- 5.11 Decay Index
- 5.12 Distance
- 5.13 dN/dS
- 5.14 Equilibrium State Frequencies
- 5.15 Evolutionary history
- 5.16 Family alignment
- 5.17 GC/AT pressure
- 5.18 Gene duplication
- 5.19 Gene loss
- 5.20 Gene tree
- 5.21 Genetic event
- 5.22 Independent Contrasts Method
- 5.23 Invariants
- 5.24 Isochore
- 5.25 minimum evolution
- 5.26 Missing Data
- 5.27 Polarity
- 5.28 Population
- 5.29 Positive Selection
- 5.30 Radiation
- 5.31 Radical
- 5.32 Relative Rate Test
- 5.33 Reticulate Evolution
- 5.34 Selective Constraint
- 5.35 Species
- 5.36 Stasis
- 5.37 Star Tree
- 5.38 Transition-Transversion Bias
- 5.39 Unrooted
- 5.40 UPGMA
- 5.41 Variation
- 5.42 Xenology
- 6 Additional terms from other domains whose meanings are consistent
- 7 Acknowledgements and History
By "evolutionary comparative analysis" we refer to the methods and foundational principles for interpreting similarities and differences as the outcome of an evolutionary process. The scope of the glossary should be such that it would serve as an effective resource for a student or a researcher (one who wishes to interpret research publications, software documentation, and interfaces), but does not duplicate common meanings from other fields
- For more information on how we define this domain, see the Background section of the EvoInfo home page.
- For details on which terms to include or avoid, see #Principles governing content.
How to improve the glossary
- define a term in the "undefined" section, then move it to the "defined" section
- directly modify a definition to improve it
- describe relations such as disjunction, synonymy, part_of and is_a, using wiki cross-refs like this:
Insertion is disjoint to [[#Deletion]]
- make it easier to maintain and disseminate this list by
- making your changes ATOMIC (one item at a time)
- maintaining the format
- sticking to principles (next section)
Principles governing content
(note: email feedback on principles to Arlin)
- What is included:
- Terms that denote general concepts (e.g., Phylogeny Inference Method, but not MrBayes).
- Terms that have a domain-specific meaning (e.g., "tree", "taxonomy").
- Composite terms only when the meaning is unexpected, but not when the meaning is obvious (e.g., "non-synonymous" means "not synonymous")
- What should not be included:
- unique instances or particulars (e.g., PAUP*; we will include these at a later stage)
- obscure, insiders-only jargon (e.g., "omega")
- terms with common meaning well outside of the domain (e.g., "integer")
- How the definition is determined
- By studying usage in articles and books (e.g., Nei and Kumar; Li and Graur; Felsenstein)
- By consulting domain experts and by soliciting feedback
- By studying the use of terms in software and data interfaces
- How synonyms, ambiguities and overlaps are handled
- we may make a term domain-specific by qualifying it, as in "Phylogenetic tree" (not just "tree") or "Organismal taxonomy" (not just "taxonomy")
- Where synonyms exist, we may choose the term
- that is most widely used by domain experts
- that conflicts least with familiar extra-domain meanings
- We can decide later not to use a term that is too ambiguous
- In the case of disputes over meanings
- Open the topic for discussion on the Discussion page
- Find examples that illustrate actual usage
- Consider ways to replace a problematic term with alternatives that cover its meanings
From population genetics, fixation of an allele is the attainment of a frequency of 1, or more rigorously, attainment of a frequency approaching some point of stability that is equal to, or nearly equal to, 1.
In common usage, "analogy" is a common term for the relation between two things (or processes) that have a simmilar pattern among their parts (or sub-processes). In evolutionary biology, "analogy" has a peculiar meaning that is restricted to cases in which the things compared are not homologous. That is, homologous structures may have the same pattern or function, but they are not called "analogous". A moth's wing and a robin's wing are said to be analogous, whereas a robin's wing and a crow's wing are not.
An entity from whom features were inherited by some #OTU of current interest. A #Parent is the closest form of ancestor. Ancestry is the reverse relation of #Descendant descendancy. The nearest ancestral node on a tree is sometimes called an "immediate" ancestor. See #Most Recent Common Ancestor. The relationship of ancestry is transitive: if A is the ancestor of B, and B is the ancestor of C, then A is the ancestor of C.
A partition of all #OTUs (in the current analytical context) into two sets. Every #Branch in a #Phylogenetic Tree defines a Bipartition. Bipartititions are used when comparing #Phylogenetic Tree topologies to assign Bootstrap Support Values or to identify shared features of Topology. Synonyms: Split
In phylogenetics, references to a "bootstrap" ("bootstrap support", "bootstrap confidence") value typically refer to a #Branch Support Value computed by bootstrap resampling (bootstrapping). Bootstrapping is a Resampling Method used to create pseudo-replicate data sets by drawing (with replacement) from the available data set. The fraction of times an outcome occurs among #Phylogenetic Trees inferred from bootstrap-resampled data sets is the Bootstrap Support value for that outcome. Thus the bootstrap support value for a #Branch is the fraction of times this #Branch is found in #Phylogenetic Trees computed from resampled data sets.
Each #Branch in a #Phylogenetic Tree defines a #Bipartition. The degree of confidence in a particular #Branch (bipartition) may be indicated by a #Branch Support value, typically a #Bootstrap Support value or a Bayesian posterior probability.
A character is a set of features related by homology, or (usually indistinguishably), it is the archetype or Platonic form underlying the "same" feature observed in different instances. In a sequence alignment or a #Character-State Data Matrix, a charater is a column. If the character has discrete states (e.g., present vs. absent; T, C, A and G), then it is a "discrete character" (likewise a "continuous character" has continuous states). See also: #Character-State; #Character-State Data Matrix; Synonyms: Column (in some contexts), Site (in some contexts)
The state of a #Character for a given #OTU. For instance, if Sequence 1 has a "G" in the 10th column of a sequence alignment, then "G" is the Character-State of the 10th Character for Sequence 1. Typically Character-States are observed values. However, the values of unobserved states, including #Ancestral states as well as #Missing Data, can be inferred using a #Transition Model applied to a #Phylogenetic Tree. Typically a #Character-State is treated as a singular definite value, however in some instances it may be conceived as a set of values present in a #Population, a distribution of values, and so on (as allowed in the NEXUS definition of a #Character-State Data Matrix
Character-State Data Matrix
A matrix of observed #Character-State data. Synonyms: Character Data Matrix, Character-State Matrix
A Clade is a set of #Species (and by extension, a set of #OTUs of any type) that includes all of the #Descendants of their #Most Recent Common Ancestor. In a rooted #Phylogenetic Tree, every #Node or #Subtree defines a Clade. An alternative definition is that a Clade includes the #Ancestor and any #Descendants whether or not they are #OTUs. Cf #Holophyletic (Systematics)
A pictorial representation of a #Phylogenetic Tree that is understood to represent only what domain experts call the #Topology, meaning the connectivity of nodes, and not the lengths of #Branches between them. Nevertheless, as actual lines must have non-zero lengths, to draw a cladogram one must apply an arbitrary convention for #Branch lengths, typically either
- make all #Branches the same length, or
- adjust #Branch lengths so that #Terminal Nodes fall on a line
#Convergent Evolution (convergence) is a pattern in which two different #OTUs reach the same #Derived #State by a different series of Evolutionary Transitions. Subclass of #Homoplasy. Considered to be disjoint with #Parallel Evolution, though the exact line of distinction is not always clear.
A #State is #Derived if it is not #Ancestor ancestral in the given context. The opposite of #Derived is #Primitive. Note that, because the use of #Ancestor is context-dependent (relative to some #OTUs of interest), #Derived is also context-dependent (for explanation, see #Primitive).
An entity that inherits features from some entity of current interest. Descendancy is the reverse relation of #Ancestor ancestry. A #Child is the closest form of descendant. The relationship of descendancy is transitive: if A is the descendant of B, and B is the descendant of C, then A is the descendant of C.
A character-based #Phylogeny Inference Method that applies the Parsimony principle to presence-and-absence (i.e., 2-state) #Characters with the restriction that gain (the #Transition from absence to presence) can happen only once for each #Character.
An evolutionary change. In the context of character analysis, an evolutionary transition is a change in the #Character-State of a #Character along a #Branch. In some contexts, "substitution", "replacement" and even "mutation" may be used as though there were synonyms for Evolutionary Transition.
See #Allele Fixation
The concept of a "gap" is ambiguous and is tied to the use of a "gap character" (often the en dash "-") in text representations of sequence alignments. In general, the "gap" represents the absence of any positively diagnosed #Character-State. As such, the gap may be interpreted as an additional #Character-State, as the absence of the #Character, or as an unknown value (#Missing Data).
General Time-Reversible Model (GTR)
Grantham's hypothesis that each species has a distinctive genome-wide #Codon Usage strategy reflecting adaptation for translation efficiency.
Horizontal Gene Transfer (see #Lateral Gene Transfer).
Homoplasy (Lankester, 1870) is any pattern in which evolutionary change occurs but does not increase differentiation. If the comparison is between a descendant and an ancestor, then the pattern is #Reversal or #Atavism. If the comparison is between two descendants, the pattern is either #Convergent Evolution (when the descendants become more similar) or #Parallel Evolution (when the descendants undergo identical changes).
Condition of a set of #Species (and by extension, #OTUs of any kind) and their #Ancestors that includes their #Most Recent Common Ancestor and all of its #Descendants. "Holophyletic group" thus is synonymous with #Clade. Subclass of #Monophyly, disjoint to #Paraphyly (sensu Ashlock).
Horizontal Gene Transfer (HGT)
Hypothetical Taxonomic Unit
A fusion of the terms for #Insertion and #Deletion that has two meanings, one based on the logic of OR (common in phylogenetics), and the other based on the logic of AND (used in mutation research, e.g., Chuzhanova, et al., 2003):
- A length difference between two aligned sequences, denoting the evolutionary occurrence of either an #Insertion OR a #Deletion during their divergence from a common ancestor.
- A complex mutational event involving the addition of some residues and the loss of others, i.e., #Insertion AND #Deletion
Lateral Gene Transfer
Incorporation of genetic material from one organism into the genome of another organism that is not its reproductive offspring is called "Lateral" or "Horizontal" gene transfer. The more typical form of inheritance is the "vertical" transfer that takes place from parent to offspring during biological reproduction. Lateral Gene Transfer is sometimes abbreviated LGT.
see #Terminal Node
A #Phylogeny Inference Method in which the objective function used to characterize a #Phylogenetic Tree (and #Transition Model) is the likelihood, which is the probability of the observed data conditional on the #Phylogenetic Tree and the #Transition Model.
A Lineage is a forward (in time) path in a #Phylogenetic Tree, representing a linear path of descent connecting an #Ancestors to #Descendant. Lineages are not determinable in the case of an un#Rooted tree.
The assumption that evolution is clock-like over some interval, typically in the sense that the expected number of #Evolutionary Transitions per unit of time is constant.
Condition of a set of #Species (and by extension, #OTUs of any kind) and their #Ancestors that includes their #Most Recent Common Ancestor. In contexts where #Monophyly is not sub-classed to #Holophyly and #Paraphyly, it often is assumed to mean #Holophyly (sensu Ashlock).
Most Recent Common Ancestor
The Most Recent Common Ancestor (MRCA; also LCA or Least Common Ancestor) of a set of two or more #Species (or, by extension, any kind of #OTU) is the most recent ancestor shared among the set, corresponding to the most proximal ancestral #Node on a #Phylogenetic Tree).
- (abstract) the process by which heritable changes in the genome occur
- a particular heritable change in a genome (e.g., the mutation causing the most common sickle-cell allele)
- the altered state resulting from a mutation, i.e., the mutant state
An asymmetry or non-uniformity in the occurrence of #Mutations categorized by position, type, effect class, or some other index variable.
The process by which inherent asymmetries in the survival and reproduction of competing forms lead cumulatively to differences in representation of these forms. Disjoint to #Random Genetic Drift.
A distance-based #Phylogeny Inference Method.
A kind of #Phylogenetic tree in which some typical restrictions are not satisfied. In some contexts, it is a synonym for un#Rooted #Phylogenetic Tree. In other contexts, it signals the presence of #Nodes with multiple parents.
A difference that has an insignificant effect on fitness. In population genetics, a fitness difference <math>s</math> is considered insignificant if <math>|s|<<1/(2PN_e)</math>, where <math>P</math> is the ploidy (one for haploids, two for diploids), and <math>N_e</math> is the effective population size. Outside of population genetics, this term may be used more loosely to indicate a difference that is thought to be unimportant. This term may be applied to a #Polymorphism, #Mutation, or #Evolutionary Transition that represents a #Neutral difference.
Operational Taxonomic Unit
The entities from which #Character-States are observed and taken as ground truths. In some cases the #OTU may be a composite of data drawn from several sources. Note that the use of "taxon" for both an #OTU and for a class in #Organismal Taxonomy is a cause of confusion.
A classification of organismal Species consisting of a nested hierarchy of classes. Traditional #Organismal Taxonomy includes named #Taxonomic Ranks and is the basis for the usual way of referring to species of organism by Genus and Species (e.g., Homo sapiens is the sapiens species of the genus Homo).
- When used as a unary modifier, i.e., when a set of one or more #OTUs is designated as "the outgroup", the outgroup is a set of #OTUs assumed on prior grounds to be a phylogenetic outlier from the complementary "ingroup" consisting of all the other #OTUs, that is, the ingroup and the outgroup are sister clades that represent two separate paths of descent from a common ancestor. Typically such an outgroup is designated for the purpose of Rooting a #Phylogenetic Tree.
- A secondary usage is to describe the relation of two sets A and B given a #Phylogenetic Tree in which A and B are non-overlapping clades.
Parallel Evolution (parallelism) is a pattern in which two different #OTUs reach the same #State by the same series of Evolutionary Transitions. Parallelism is a subclass of #Homoplasy and is considered to be disjoint with #Convergence, though the exact line of distinction is not always clear.
Condition of a set of #Species (and by extension, #OTUs of any kind) and their #Ancestors that includes their #Most Recent Common Ancestor and some but not all of its #Descendants. Subclass of #Monophyly, disjoint to #Holophyly (sensu Ashlock). For instance, the reptile group is paraphyletic because, while it s common ancestor was a reptile, some of its descendants are birds not included in the reptile.
A method for finding the minimum transitions to account for a #Character given a #Phylogenetic Tree, and by extension, a character-based #Phylogeny Inference Method in which the inferred #Phylogenetic Tree (the "maximum parsimony tree") is the #Phylogenetic Tree that minimizes #Evolutionary Transitions over all #Characters.
A Phylogenetic Tree represents evolutionary paths of descent-with-modification from common ancestors. Typically a Phylogenetic Tree is assumed to be a connected, directed, acyclic graph in which Nodes have no more than one parent and the directionality of each edge is from the #Root toward the #Terminal Nodes. When domain scientists wish to relax these restrictions due to conditions of not knowing the #Root, or of allowing for multiple parentage (cf. #Reticulate Evolution, #Lateral Gene Transfer), they favor the term "#Network", though this usage once again does not correspond to the meaning assigned to this term in the field of graph theory.
Phylogenetic Tree Topology
Phylogeny Inference Method
A method of inferring an evolutionary history (#Phylogeny. Phylogeny inference methods may generate a #Phylogenetic Tree as well as #Reconstrutions of #Ancestral #Character-States, using inputs based on observed data. They fall into two broad classes: distance-based methods that use a #Distance Matrix as input, and character-based methods that use a #Character-State Data Matrix as input. Of the character-based methods, some are rule-based (#Parsimony, #Invariants), while others are probabilistic and depend on a #Transition Model that must be specified explicitly and evaluated in terms of Likelihood or Bayesian Posterior Probability.
The presence, in a single Species or #Population, of more than one #Character-State for a given #Character. In the field of population genetics, this term sometimes is restricted such that a genetic locus is not considered Polymorphic unless the most frequent state has a frequency below 95 % or 99 % (i.e., in this case, polymorphism is a restricted subclass of #Population Variation).
A #State is #Primitive if it is #Ancestor ancestral in the given context. The opposite of #Primitive is #Derived. Note that, because the use of #Ancestor is context-dependent (relative to some #OTUs of interest), #Primitive is also context-dependent, e.g., when comparing human locomotion to mouse locomotion, human bipedalism is derived (since the ancestor walked on four legs), but when comparing human locomotion and chimp locomotion, it is unclear whether bipedalism is derived, since the human-chimp ancestor might have been bipedal (in which case, human bipedalism would be the primitive state, and chimp knuckle-walking the derived state).
Random Genetic Drift
The process by which stochastic asymmetries in survival and reproduction of competing forms lead cumulatively to differences in representation of these forms. Disjoint to #Natural Selection.
see #Taxonomic Rank
The #Phylogenetic Tree for a gene family may conflict with the #Phylogenetic Tree for the implicated species due to events of #Gene Duplication and #Gene Loss that occurred in its history. A Reconcile Tree (Reconciled Tree) is a special kind of #Phylogenetic Tree that reconciles a gene #Phylogenetic Tree with a species #Phylogenetic Tree by means of hypothesized events of #Gene Duplication and #Gene Loss. In principle, the concept of a "Reconcile Tree" might be extended to include events of #Lateral Gene Transfer (another source of conflicts between gene and species #Phylogenetic Trees), but this has not been attempted.
In one sense, a synonym for #Evolutionary Transition, and in another sense, an ambiguous sub-class of #Evolutionary Transition. In molecular evolution, there is a tendency to refer to #Evolutionary Transitions in sequence evolution as "substitutions" when they refer to nucleotide #Character-States, and "replacements" when they refer to amino acid #Character-States (at one time, this was the official editorial policy of the journal Molecular Biology and Evolution). In population genetics, an #Evolutionary Transition may be referred to as an "allele replacement" or "allele substitution" (e.g., Nei, 1987, p. 421), emphasizing the population-genetic mechanism in which one allele replaces another as the wild-type allele (via #Mutation and #Fixation).
The occurrence of an #Evolutionary Transition that is the reverse of an earlier transition. Note the distinction from #Reversion: all reversals return to an ancestral state, but not all #Reversions are the reverse of a previous transition, e.g., G to C to A to G is a #Reversion but none of the individual transitions (G to C, C to A, A to G) are reversed; G to C to G is both a #Reversion and a reversal.
See #Natural Selection.
A difference that is invisible or has no phenotypic effect. Applied to a #Polymorphism, #Evolutionary Transition, or #Mutation. When applied to nucleotide differences in protein-coding genes, it has the same meaning as #Synonymous.
A #Phylogenetic Tree derived from a set of partially overlapping, smaller, "source" #Phylogenetic Trees. Supertree methods are used when applying character-based #Phylogeny Inference Methods to the complete set of data would be too compute-intensive, or when #Missing Data would prevent an analysis using the same #Characters for all #OTUs.
Taxonomic Rank is a ordered categorical descriptor applied to the classes of #Organismal Taxonomy. A class of a given rank may contain only classes of lower rank. The traditional ranks in descending order are: Kingdom, Phylum, Class, Order, Family, Genus and Species. In the 1980's, there were several conflicting proposals to extend this system upward to include a rank higher than Kingdom, variously called "Urkingdom" (Woese, et al), "Domain" (Woese, et al.) or "Empire" (Cavalier-Smith).
The nodes of a #Phylogenetic Tree that have no children. Typically Terminal Nodes in a #Phylogenetic Tree correspond to #OTUs with their observable properties, while internal nodes correspond to ancestors. However, in the case of simulations or evolution-in-the-lab, an internal node may be associated with known properties. Some #Reconcile Trees have terminal nodes that represent inferred events of #Gene Loss.
- A purine-to-purine or pyrimidine-to-pyrimidine change in nucleotides: see #Nucleotide Transition
- An evolutionary change in the state of a character: see #Evolutionary Transition
A model of rates or probabilities of Evolutionary Transitions, typically defined for use in a first-order Markov transition model.
pertaining to root of tree?
opposite of divergent, looking at a branching process on the reverse time scale
note measures RSCU, CAI
a measure of between-character consistency
tree based on combining multiple trees. misuse of "consensus". not the same as supertree.
Applied to characters or to transitions, implicating minor changes or characters that undergo such changes. opposite of radical.
Generally, in technical writing, a "constraint" signifies a condition or relation that must be satisfied, often in the context of an optimization or satisfaction problem. In evolutionary biology, this term may be used with a qualifier such as "developmental constraint" or "selective constraint", with considerable ambiguity as to what this usage signifies. Thus, there is no clear domain-specific meaning of this term.
this sounds to me like Step Matrix, with the difference that step implies non-negative integers while cost implies real numbers.
cf. Retention index, Compatibility
typically the distance between otus
ration of non-synonymous to synonymous rate. usually based on a particular model for normalization.
Equilibrium State Frequencies
distribution of characters expected at equilibrium. often used in markov transition models.
phylogeny in the broad sense
sequence alignment for a sequence family
an asymmetry in mutation or in evolutionary changes, favoring GC over AT (or vice versa).
mutation or evolutionary change resulting in additional copy of gene
loss of a gene, typically implying either deletion or silencing
tree reflects the evolutionary history of genes, not the species of origin
Independent Contrasts Method
method of assessing covariance by reducing phylogenetic distribution pattern into independent comparisons (contrasts)
a phylogenetic inference method based on invariants (domain-specific application of more general term from numeric analysis)
local compositional area in chromosomes, characteristic of warm-blooded animal genomes.
phylo inference method
absence of character state data due to deletion or lack of information
assigned to transitions that have a direction (i.e., a different rate or cost in the forward vs. reverse direction); polarizing differences means determining which (if any) state is ancestral.
a reproducing population, consisting of interbreeding individuals.
differential reproduction (selection) viewed relative to the variant whose frequency increases
episode of rapid or repeated cladogenesis
opposite of conservative
Relative Rate Test
a simple test to correct for phylogenetic structure when assessing rate constancy, in which, given the tree (A, (B,C)), the distances (or inferred changes) from A to B are compared to those from A to C.
pattern of evolution in which separate lineages fuse again
relative to an imaginary case in which there is no selection, a condition of a reduced rate of change due to the probability of deleterious effects.
assemblage of actually or potentially reproducing organisms, consisting of one or more populations.
tree with a single ancestor node that is the parent of all otus
is_a Mutation Bias
Not rooted, applied to trees.
A phenetic clustering method. Arguably, a phylogeny inference method based on using distances.
too ambiguous? population variation is one clear usage. others are vague
relation of homology via lateral transfer
Additional terms from other domains whose meanings are consistent
From statistics and applied maths
- likelihood ratio test;
- Akaike information criterion; * odds ratio; bootstrap resampling;
- Monte Carlo methods;
From biology, systematics, genetics, and evolution
From molecular biology and bioinformatics
- aligned sequences
- unaligned sequences
From computer science and maths
Acknowledgements and History
- June, 2006, Aaron Mackey started a glossary (19 domain concepts and a few other terms) for the group that spawned the NESCent evolutionary informatics working group.
- September, 2007, Arlin Stoltzfus expanded the concept glossary to 40 defined terms and 22 undefined terms.
- 12 October, 2007, the concept glossary was released to the NESCent evolutionary informatics working group
- November, 2007, EvoInfo working group meeting (12th to 14th) and follow-ups
- terms added by Julie Thompson, Enrico Pontelli, Arlin Stoltzfus
- reformatted to wiki to allow easier cross-referencing
- dozens of cross-references added (not complete)
- about 50 defined terms added (Arlin)