- 1 Overview
- 2 VoCamp related meeting plan
- 3 Locations
- 4 Hackathon-related ideas
- 5 Proposal for a Phyloinformatics VoCamp
NESCent has some funds and is open to the idea of another hackathon. Past hackathons have been 15 to 20 people from outside NESCent, along with a handful from inside NESCent.
We decided to focus on developing vocabulary and ontology with a diverse group of stakeholders.
Background: drivers and issues
We don't know precisely what this group will choose to focus on, but we need to articulate some of the drivers and state some of the issues to be resolved.
For instance, deciding how we are going to designate taxonomic identifiers is critical. Data integration depends on being able to integrate across common variables. In the genomics world, these are things like genbank accession numbers, species names (or NCBI taxon ids), and sequences, e.g., my colleague John Moult integrates SNP data, function annotations, and protein structure by way of sequence matches and accession numbers. In the larger world of comparative biology, the integrating variables would include (in addition to genbank accessions and species names) other taxon identifiers, specimen (and collection) ids, geographic coordinates, and so on.
In development of the PhyloWS standard, we are working on specifying the available query terms. For example, a user may want to find:
- subtrees descended from a given internal node
- trees inferred using maximum likelihood
- fully resolved (binary) trees
But we need terminology to define these concepts. Ideally, these terms would be in an external ontology. This would also allow the NeXML returned from a PhyloWS query to contain these concepts, linked as metadata through the ontology.
Feel free to expand anything in the list into its own subsection
- decide on an approach to representing descriptions of studies (probably based on OBI)
- clarify relations in CDAO, following BFO and REL principles
Soliciting and choosing participants
We need to consider how we will choose participants and prepare for the meeting. We may need to pick very carefully to achieve credibility if we want to promote standards. This looks like a diverse group.
Preparing materials for the meeting
It would be a failure if the group got together and split into tiny pieces because there were not enough common interests. We may need to assemble test cases that could be used to evaluate solutions, e.g., test cases of taxonomic disambiguation or cross-mapping.
What will be the structure of the meeting? Open Space? Agenda?
- Cost per person:
- $ 900 from major US airport to Montpellier
- $ 110 per night lodging
- Meeting facilities:
- essentially free
- TDWG annual meeting in Montpelier (http://www.tdwg.org/) November 9 to 13
- TDWG attendees would need lodging costs
- CDAO group in Strasbourg (Julie Thompson); collaborator Pontarotti in Marseilles has developed an ontology of "genetic events" in evolution.
- Ontologies group at U. Manchester is a cheap flight away.
- some relevant initiatives & projects
- Cost per person:
- Meeting facilities:
- NESCent: Vision, Lapp, Balhoff, Swofford, Scherle
- Cost per person:
- Meeting facilities:
- Tucson, AZ is 3 or 4 hr away by car (iPlant Collaborative; Maddison will have moved to Oregon by Nov; Mike Worobey in EEB does viral phylogenetics)
- Los Alamos (LANL HIV db) is 3 hr away by car)
- NMSU is home of Pontelli, Chisham
- challenges or disadvantages
- airport is an hour away
Projects focused on consolidating our gains and serving the community of users:
- polish up demo projects from dbhack1. The dbhack1 projects were promising but incomplete. Solid well documented demonstration projects are needed to expose our interop technologies.
- set up an EvoIO portal (translation, data set curation, etc)
- develop an online course complete with information resources, demos, and assignments
Projects focused on building foundations and serving the community of developers:
- widen the domain by including viral phylogenetics and molecular epidemiology
- ontology, including sticky problems (CDAO relations and upper-level categories) and annotation support (names of programs and file formats)
- transition model language
phylo interop portal
the strategic focus of the portal would be interop, but the portal could support other community-building activities such as blogs, bookmarking, forums, etc.
- provide users with centralized resources
- demonstrate useful, working aspects of interop technologies
- illustrate benefits of integrative or large-scale analyses
- testbed for trying out new concepts and for debugging
- increase exposure of project to increase chances of funding
- format interconversion
- triple store for download
- visualization - second
- data set integration wizard
- annotation support for curation, metadata
- analysis operations (implemented by reasoner)
- how to get this done with limited resources
- get more players involved by conceiving this broadly
- provide hosting to some projects where mutually beneficial
- use the hackathon mechanism to get started
- use CREST funds to hire graduate student
- prepare in advance to take advantage of GSoC mechanism
- work with NSF PIs to get interop-related supplements (e.g., MrBayes)
polish up projects
- phylowidget/viz improvements
- clean up and generalize interface; complete modularization
- integrate with other projects with an outward facing PhyloWS interface
- write-back capability via PhlyoWS
Proposal for a Phyloinformatics VoCamp
Co-leaders. The group of organizers preliminarily consists of N. Cellinese, K. Cranston, H. Lapp, E. Pontelli, Sheldon McKay, A. Stoltzfus, and R. Vos, and is chaired by A. Stoltzfus (corresponding PI).
Synopsis. Standard, interoperable, controlled vocabularies and ontologies are key to the ability to integrate and compute over data across fields, experimental systems, and protocols. Ensuring that these artifacts continuously evolve to meet changing research demands requires an open, community-based development process. At a recent NESCent-sponsored hackathon on Evolutionary Database Interoperability, ontologies and vocabularies that meet the needs of diverse community resources and tools emerged as the key gap among the three components of the emerging EvoIO stack of interoperability standards. Filling this gap on a sustainable basis requires a diverse community of domain experts, users, and stakeholders with a shared awareness of, and commitment to, knowledge-based standards. To begin building such a community, we propose a -style meeting for investigators to create and develop ontologies and lightweight vocabularies in support of integration and semantic cross-linking of evolutionary data with its many related fields. To take advantage of such cross-initiative synergy, and to foster better communication and knowledge exchange between them, we propose to co-localize the event with the annual meeting of the .Background. The work of the Evolutionary Informatics Working Group at NESCent on addressing obstacles to interoperability of evolutionary data and tools has given rise to a set of emerging standards for transmission of and access to data and its semantics in a predictable and programmable manner. Specifically, the set consists of a rigorously defined and validatable syntax standard for phylogenetics data and trees with embedded and semantically rich metadata ( ), a standard programmable interface to online phylogenetic data resources (PhyloWS), and an ontology defining the terms and concepts used in comparative evolutionary analysis and the relationships between those ( ).
The working group concluded its work in March 2009 with a hackathon event focused on interoperability of evolutionary data resources. The event was successful in multiple ways. It brought together developers of the EvoIO technologies and related projects with database experts from key online data resources in evolutionary biology, significantly increasing awareness of interoperability obstacles as well as preferred approaches to overcoming obstacles. The event also raised the profile and capabilities of the EvoIO stack (NeXML, CDAO and PhyloWS), and demonstrated that, with a modest amount of training and effort, data providers can improve interoperability, with benefits for data providers and for end users. Furthermore, the group of collaborators who subsequently formulated the EvoIO community vision proposed to NSF emerged from this event.
As another key outcome of the event, participants from various subgroups repeatedly identified a gap in the availability of a sufficiently expressive ontology, or set of ontologies and vocabularies, along with community mechanisms and infrastructure to sustain their continued development and evolution. This was confirmed by several subsequent efforts to adopt some of the standards, for example incorporating PhyloWS and NeXML-support into the next-generation version of the community resource TreeBASE.
Motivation: Need to extend ontologies. Online repositories of evolutionary data contain data and metadata that far exceed the scope of the current CDAO ontology. The overall goal of the EvoIO stack is to allow this data to be accessed, searched, retrieved, and repurposed programmatically. The NeXML and PhyloWS projects allow describing, sharing, and querying data from diverse online databases, but their development is being hampered by a lack of controlled vocabulary and ontologies necessary to transport the semantics in an interoperable manner. Examples that have already been identified through the work of hackathon and EvoInfo participants include metadata on experimental protocols, ontology-based annotation of phenotypes, and taxonomic affiliations of OTUs.
Even if the EvoIO stack projects agree on terminology, developing sustainable solutions to these problems requires coordination and direct involvement of a much larger community of stakeholders. A sustainable solution requires nurturing a community dynamic in which domain experts, users, and developers alike know the value of shared terminology, and know how to contribute to its development.
We propose to jump-start such a community dynamic by holding a list of upcoming and previous VoCamps), and hold significantly potential to foster collaborative and open development and community cohesion for ontologies as hackathons have been shown capable of for open-source software development.-style event. A VoCamp is similar in conception to a hackathon in the sence of being an intense, hands-on, working meeting with face-to-face interactions between a diverse group of people who create an intellectually fertile stimulating atmosphere. Instead of developing software source code, it focuses on issues of vocabulary and ontology design, development, and application. VoCamps have emerged only recently (in 2008), but have since spread rapidly (see the online
Meeting preparation. To maximize the productivity of the event, it is important that those who attend are committed to, and capable of, making substantive contributions to the development process, and that the participants represent a balanced mix of ontological engineers, logicians, domain experts, as well as developers who would consume and apply the ontologies.
We propose to hold this meeting co-incident with the Bio-Health Informatics and the Information Management Groups at the University of Manchester, which comprise some of the world's leading ontologists and semantic web experts. We expect the TDWG-related venue would be attractive to a variety of initiatives including Darwin core, Biological Descriptions, Taxonomic names and concepts, GBIF, EOL, Observational Data, and DataOne. Aside from these opportunities to connect disparate communities facing similar issues, holding the event at the TDWG meeting would double as an ongoing activity of the TDWG Phylogenetics Standards Interest Group, which is co-led by two members of the organizing group (Lapp and Cellinese).in Montpellier, France. This would allow us to take advantage of opportunities for synergy with the recent shift of TDWG activities towards shared vocabularies and ontology development, as well as for broadening the nascent EvoIO community to biodiversity informatics practitioners, which includes information scientists working in museums, ecology, and conservation. A European location would also be very cost-effective for some of the CDAO developers, who are based in Strasbourg, and for involving the
Additional participants will be recruited through an open call for participation disseminated to data providers, mailing lists for the EvoIO Stack, the Scientific Observations Network (GBIF, the Society for Systematic Biology, and the EvolDir and EcoLog mailing lists.), TDWG mailing lists,
Meeting agenda. As successfully practiced previously for the NESCent-sponsored hackathons, the exact agenda will be developed by the participants, partly in advance through teleconferences and online electronic media, and partly on-site through an Open Space activity. We anticipate, however, that the following activities and tasks will be needed to ensure a productive event for all participants.
- Boot-camps on ontology design and engineering, ontology languages and their restrictions, entailment and reasoning over ontologies, and infrastructure for collaborative development of ontologies.
- Identification of focus areas for vocabulary development and term definition.
- Identification of targets of opportunity for cross-project and cross-community synergy.
Similar as in hackathons, the participants will break into smaller subgroups that collaboratively work on their chosen development targets. The total event duration is envisioned to be between 4-4.5 days. The event will conclude with a wrap-up session, and if held at the TDWG Annual Meeting, a report will be scheduled to be presented afterwards to the TDWG Conference audience.
Expected outcomes. We expect that the event will have a substantive impact on multiple ontology development efforts, stakeholder communities, and interoperability initiatives, by connecting previously disparate communities with shared objectives, sharing knowledge, and by actually building out existing ontology resources in terms of ontological rigor, semantic richness, and modularity that supports effective reuse. Specifically for evolutionary data interoperability, we expect the event to result not only in a much richer and well-defined CDAO that meets the immediate needs of online data providers and aggregators, but also in a much improved alignment of CDAO design principles with initiatives from ecology (such as), biodiversity (such as and the ), and genetics / biomedicine (such as ).
We anticipate that the event, if successful, will give rise to similarly structured follow-up events organized by these other communities; although subject-focused ontology development sprints have taken place for OBO ontologies (such as for specific regions of an anatomy), more inclusive VoCamp-style events have not yet in any of those. If the EvoIO Community Network is funded, the expected outcomes of this event will provide the network with a substantial head-start both in terms of standards development as well as community diversification and engagement.